Folic Acid

Thickeners & StabilizersCAS: 59-30-3

This is what the ingredient is.

Folic acid is the synthetic form of folate (Vitamin B9), a water-soluble vitamin naturally found in leafy greens, legumes, and fortified grains.

Here is why it shows up on the label.

Nutrient fortification mandated in enriched grain products. Essential for DNA synthesis and cell division. Critical during pregnancy to prevent neural tube defects.

Here is what food agencies say.

FDA mandated fortification in enriched grain products since 1998. RDA: 400 mcg/day; 600 mcg during pregnancy. Upper limit: 1000 mcg/day from fortified food/supplements. Approved globally.

Here is what research has found.

Fortification program dramatically reduced neural tube defects by 35%. Essential for rapidly dividing cells. High intake may mask vitamin B12 deficiency. Studies in JAMA document public health impact.

Here are a few things worth knowing.

Supplementation above upper limit may mask vitamin B12 deficiency (can lead to irreversible nerve damage if untreated). Some research suggests very high intakes might affect immune function or cancer risk, though evidence mixed. Fortification levels are safe and highly beneficial, especially for women of reproductive age.

Sources

  • FDA Fortification Mandate
  • JAMA 2001
  • NIH Folate Fact Sheet
  • CDC Neural Tube Defect Data

How to read this page

We publish plain facts about this ingredient so a label is easier to read. This is not medical advice, and it is not a recommendation to buy, avoid, or use anything. For a personal health question, talk with a clinician who knows your history.

v1.0Updated 9/12/2026