Epsilon-Polylysine
PreservativesCAS: 28211-04-3
This is what the ingredient is.
Epsilon-polylysine (ε-PL) is a natural antimicrobial peptide produced by bacterial fermentation.
Here is why it shows up on the label.
Broad-spectrum natural preservative effective against bacteria, fungi, and some viruses. Used in Japan since 1989.
Here is what food agencies say.
The FDA lists it as Generally Recognized as Safe. Approved in Japan, US, and other countries. EFSA evaluation ongoing.
Here is what research has found.
Natural fermentation product. Studies show effectiveness against food pathogens. Good safety profile.
Here are a few things worth knowing.
Generally well-tolerated. May cause mild bitter taste at high concentrations.
Sources
- FDA GRAS Notice
- Japanese Food Safety Commission
- Journal of Antimicrobial Chemotherapy
How to read this page
We publish plain facts about this ingredient so a label is easier to read. This is not medical advice, and it is not a recommendation to buy, avoid, or use anything. For a personal health question, talk with a clinician who knows your history.
v1.0Updated 9/12/2026